Uniform molecular weight polymers
US6803438B1 · kind B1 · utility
Assignee
Inventors
Key dates
| Filing date | Aug 9, 2002 |
| Grant date | Oct 12, 2004 |
| Priority date | — |
| Expiry date | Aug 9, 2022 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC08F246/00
- WIPO fieldMacromolecular chemistry, polymers
- WIPO sectorChemistry
Abstract
A polymer comprising the unit (I) wherein R is selected form the group consisting of hydrogen, C1-C18 alkyl, C1-C18 aralkyl, C1-C18 alkaryl, carboxylic acid, carboxy-C1-6alkyl, or any one of the C1-C18 alkyl, C1-C18 alkenyl, C1-C18 aralkyl, C1-C18 alkaryl substituted with a heteroatom within, or attached to, the carbon backbone; R1 is selected from the group consisting of hydrogen, C1-C6 alkyl groups; X is an acylating agent and wherein the polymer has a polydispersity of less than 1.4, preferably less than 1.2 and a molecular weight (Mw) of less than 100,000, the polymer is preferably made by controlled radical polymerization and is useful in the production of polymer drug conjugates with desirable biological profiles.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.