Detection of biological molecules using chemical amplification and optical sensors
US6804544B2 · kind B2 · utility
725Cited by
45References
24Claims
0Family size
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Key dates
| Filing date | Aug 21, 2001 |
| Grant date | Oct 12, 2004 |
| Priority date | — |
| Expiry date | Jun 22, 2022 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q1/005
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
Methods are provided for the determination of the concentration of biological levels of polyhydroxylated compounds, particularly glucose. The methods utilize an amplification system that is an analyte transducer immobilized in a polymeric matrix, where the system is implantable and biocompatible. Upon interrogation by an optical system, the amplification system produces a signal capable of detection external to the skin of the patient. Quantitation of the analyte of interest is achieved by measurement of the emitted signal.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.