Multiple unit controlled food effect-independent release pharmaceutical preparations and method for preparing the same

US6805881B1 · kind B1 · utility

Assignee

• BAYER HEALTHCARE LLC · DE

Inventors

• Venkata-Rangarao Kanikanti · Leverkusen, DE
• Roland Rupp · Bensberg, DE
• Erich Brendel · Solingen, DE
• Claus Weisemann · Apex, US
• Ernst Chantraine · Walnut Creek, US

Key dates

• Filing date: Apr 23, 2001
• Grant date: Oct 19, 2004
• Expiry date: Apr 23, 2021

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P9/10
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention relates to orally administrable multiple-unit sustained-release dose forms having controlled agitation-independent release of active compound and processes for their production using a selected erodable hydrophilic polymer (HPC) and a limitation of the maximum size of the active compound-containing polymer particles to ≦3 mm.