Dihydropteridinones, processes for preparing them and their use as pharmaceutical compositions

US6806272B2 · kind B2 · utility

Assignee

• BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG · DE

Inventors

• Eckhart Bauer · Biberach, DE
• Steffen Breitfelder · Aßmannshardt, DE
• Christian Eickmeier · Mittelbiberach, DE
• Matthias Grauert · Ingelheim am Rhein, DE
• Matthias Hoffmann · Mittelbiberach, DE
• Thorsten Lehmann-Lintz · Ochsenhausen, DE
• Gerald Pohl · Gau-Algesheim, DE
• Jens Juergen Quant · Guntramsdorf, AT
• Norbert Redemann · Biberach, DE
• Gisela Schnapp · Biberach an der Riß, DE
• Martin Steegmaier · Wien, AT

Key dates

• Filing date: Aug 23, 2002
• Grant date: Oct 19, 2004
• Expiry date: Nov 20, 2022

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D475/00
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The present invention relates to new dihydropteridinones of the formula (I) wherein the groups X, R1, R2, R3, R4, R5 and R7 have the meanings given in the claims and the specification, the isomers thereof, processes and intermediates for preparing these dihydropteridinones as well as the use thereof as pharmaceutical compositions.