Small-molecule inhibitors of interleukin-2
US6806279B2 · kind B2 · utility
19Cited by
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19Claims
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Key dates
| Filing date | Dec 17, 2001 |
| Grant date | Oct 19, 2004 |
| Priority date | — |
| Expiry date | Dec 17, 2021 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Compounds of formulae I and I′, methods of making them, pharmaceutical compositions containing them, and methods for their use. The compounds are antagonists of IL-2/IL-2R binding; and are useful for the treatment of interleukin-2 mediated diseases, such as autoimmune diseases (such as rheumatoid arthritis, multiple sclerosis, uveitis, and psoriasis), allograft rejection, and graft-versus-host disease.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.