Peptide inhibitor of TGF-&bgr; growth factors
US6806358B1 · kind B1 · utility
2Cited by
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2Claims
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Key dates
| Filing date | Dec 16, 1998 |
| Grant date | Oct 19, 2004 |
| Priority date | — |
| Expiry date | Dec 16, 2018 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S530/858
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A potent peptide inhibitor (SuperSog) of TGF-&bgr; family growth factor signalling, peptide variants thereof and nucleotide coding sequences therefor are provided by the invention. The Super-Sog peptide comprises a fragment of the Drosophilia short gastrulation (Sog) gene which includes the CR-1 cysteine-rich repeat of Sog. Methods and compositions for use of Super-Sog in therapeutic and diagnostic applications are also provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.