Fluorescence detection with increased dynamic range
US6806460B2 · kind B2 · utility
7Cited by
13References
14Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | May 31, 2002 |
| Grant date | Oct 19, 2004 |
| Priority date | — |
| Expiry date | Nov 19, 2022 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01J3/36
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The light detection system includes at least two light detection elements. Each element is responsive to a selected light color in a first mode, and each element has a different sensitivity and is responsive to a single color in a second mode for enhanced dynamic range. A preferred embodiment includes four light detectors for responding to four separate colors or for responding with enhanced dynamic range to two colors. Embodiments are disclosed using a mirror/beam splitter arrangement to switch between modes and an embodiment including dichroic filters serving as fractional beam splitters.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.