Wound healing compositions and methods using tropoelastin and lysyl oxidase
US6808707B2 · kind B2 · utility
17Cited by
31References
10Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Feb 4, 2000 |
| Grant date | Oct 26, 2004 |
| Priority date | — |
| Expiry date | Feb 4, 2020 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Y104/03013
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides compositions and methods for promoting wound healing. The composition comprises virgin monomers of tropoelastin and lysyl oxidase. When the lysyl oxidase comes in contact with the tropoelastin, cross-linking of the tropoelastin monomers will occur to form elastin. Contacting the tropoelastin and lysyl oxidase together and applying the mixture to a wound before substantial cross-linking has occurred promotes wound healing by holding the damaged tissue together, increasing the rate of healing, and decreasing the amount of scarring.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.