Directionally cloned random cDNA expression vector libraries, compositions and methods of use
US6808906B2 · kind B2 · utility
53Cited by
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15Claims
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Key dates
| Filing date | May 8, 2002 |
| Grant date | Oct 26, 2004 |
| Priority date | — |
| Expiry date | May 8, 2022 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2800/70
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention provides random cDNA expression vector libraries, comprising expression vectors which comprise random cDNAs positioned in sense orientation. Also provided are random cDNA expression vector libraries, comprising expression vectors which comprise random cDNAs positioned in antisense orientation. Methods for producing these libraries through directional cloning of random cDNAs are also provided. Also provided herein are methods of using these libraries to screen for agents capable of modulating cell phenotype in desirable ways.
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