(Halo-benzo carbonyl)heterocyclo fused phenyl p38 kinase inhibiting agents

US6809199B2 · kind B2 · utility

Assignee

• MERCK & CO., INC. · US

Inventors

• James B. Doherty · New Milford, US
• John E. Stelmach · Westfield, US
• Meng-Hsin Chen · Xinpi, TW
• Luping Liu · Gurnee, US
• Julianne A. Hunt · Scotch Plains, US
• Rowena D. Ruzck · Old Bridge, US
• Joung Goulet · Westfield, US
• David Wisnoski · Quakertown, US
• Swaminathan Natarajan · Scotch Plains, US
• Kathleen M. Rupprecht · Cranford, US
• Jianming Bao · Scotch Plains, US
• Shouwu Miao · Edison, US
• Xingfang Hong · Westfield, US
• Peter J. Sinclair · Highland Park, US
• Florida Kallashi · Yonkers, US

Key dates

• Filing date: Dec 17, 2001
• Grant date: Oct 26, 2004
• Expiry date: Dec 17, 2021

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D487/08
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Compounds described by the chemical formula (I) or a pharmaceutically acceptable salt thereof: are inhibitors of p38 useful in the treatment of inflammatory diseases such as arthritis.