Defective recombinant adenoviruses expressing cytokines for antitumor treatment
US6811774B2 · kind B2 · utility
10Cited by
3References
1Claims
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Key dates
| Filing date | Dec 3, 1998 |
| Grant date | Nov 2, 2004 |
| Priority date | — |
| Expiry date | Dec 3, 2018 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2710/10343
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A recombinant nucleic acid used for the production of a defective adenovirus containing an inserted sequence coding for a cytokine under the control of a promoter in the genomic sequence of the recombinant adenovirus. This recombinant adenovirus is useful in the preparation of anti-tumoral drugs which can be directly injected into the tumor of the host.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.