Patent · US Expired

Cancer diagnostic method based upon DNA methylation differences

US6811982B2 · kind B2 · utility

2Cited by
4References
10Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMar 28, 2002
Grant dateNov 2, 2004
Priority date—
Expiry dateMar 28, 2022

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12Q1/6858
  • WIPO fieldBiotechnology
  • WIPO sectorChemistry

Abstract

There is disclosed a cancer diagnostic method based upon DNA methylation differences at specific CpG sites. Specifically, the inventive method provides for a bisulfite treatment of DNA, followed by methylation-sensitive single nucleotide primer extension (Ms-SNuPE), for determination of strand-specific methylation status at cytosine residues.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.