Process for the isolation and purification of mevinolin
US6812007B1 · kind B1 · utility
0Cited by
1References
2Claims
0Family size
Inventors
Key dates
| Filing date | Apr 19, 2000 |
| Grant date | Nov 2, 2004 |
| Priority date | — |
| Expiry date | Apr 19, 2020 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12P7/62
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
In a process for preparing mevinolin by fermentation of a biomass in a fermentation liquor, which includes dissolving mevinolin from the biomass into the fermentation liquor, and separating the biomass from the fermentation liquor to obtain a separated fermentation liquor, separating the mevinolin from the separated fermentation liquor, and recovering the end product, the improvement which comprises carrying out the dissolving at a pH between 7.5 and about 10, and the separating of the mevinolin is carried out at a pH between about 4.5 and about 1.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.