Indole derivatives and their use for the treatment of malignant and other diseases based on pathological proliferation

US6812243B2 · kind B2 · utility

Assignee

• Zentaris GmbH · DE

Inventors

• Siavosh Mahboobi · Regensburg, DE
• Sabine Kuhr · Westerstede, DE
• Herwig Pongratz · Regensburg, DE
• Alfred Popp · Unterhaching, DE
• Harald Hufsky · Gaimersheim, DE
• Frank-D Bohmer · Vacha, DE
• Steffen Teller · Jena, DE
• Andrea Uecker · Neuengönna, DE
• Thomas Beckers · Konstanz, DE

Key dates

• Filing date: May 3, 2002
• Grant date: Nov 2, 2004
• Expiry date: Dec 23, 2022

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D491/14
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The invention relates to tyrosine kinase inhibitors of the bis-indolyl compound type of the general formula I: pharmaceuticals containing them and their use for the treatment of malignant and other diseases based on pathological cell proliferation.