Carboxamide-substituted phenylurea derivatives, process for their preparation and their use as medicaments

US6812250B2 · kind B2 · utility

Assignee

• Aventis Pharma Deutschland GmbH · DE

Inventors

• Elisabeth Defossa · Idstein, DE
• Thomas Klabunde · Frankfurt, DE
• Hans-Joerg Burger · Morristown, US
• Andreas Herling · Bad Camberg, DE
• Erich Von Roedern · Hattersheim, DE
• Stefan Peukert · Frankfurt am Main, DE
• Alfons Enhsen · Lennestadt, DE
• Armin Bauer · Pocking, DE
• Bernd Neises · Offenburg, DE
• Karl-Ulrich Wendt · Frankfurt, DE

Key dates

• Filing date: May 24, 2002
• Grant date: Nov 2, 2004
• Expiry date: May 24, 2022

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07C2602/10
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention relates to carboxamide-substituted phenylurea derivatives and their physiologically tolerated salts and physiologically functional derivatives.Compounds of the formula I in which the radicals have the stated meanings, and the physiologically tolerated salts thereof and process for their preparation are described. The compounds are suitable, for example, for treating type II diabetes.