Patent · US Expired

System, method, and product for dynamic noise reduction in scanning of biological materials

US6813567B2 · kind B2 · utility

15Cited by
40References
62Claims
0Family size

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Inventors

Key dates

Filing dateNov 25, 2002
Grant dateNov 2, 2004
Priority date
Expiry dateNov 25, 2022

Classification

  • Technology area (CPC G)Physics
  • CPC primaryG16B25/00
  • WIPO fieldMeasurement
  • WIPO sectorInstruments

Abstract

Systems and methods are described for processing an emission signal, such as a fluorescent signal, to compensate for noise in an excitation beam, such as a laser beam. As one example, a scanning system is described that includes an excitation signal generator that provides an excitation signal having one or more representative excitation values representative of an excitation beam; an excitation reference provider that provides at least one excitation reference value; a normalization factor generator that compares the excitation reference value to at least one representative excitation value, thereby generating a normalization factor; and a comparison processor that adjusts at least one emission value corresponding to the at least one representative excitation value based, at least in part, on the normalization factor.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.