Patent · US Expired

Supramolecules containing binding and therapeutic molecules bound to hybridized nucleic acids

US6814964B2 · kind B2 · utility

27Cited by
12References
25Claims
0Family size

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Key dates

Filing dateMar 25, 2002
Grant dateNov 9, 2004
Priority date
Expiry dateJul 6, 2022

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY10S977/907
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

A supramolecule has a first supramolecular component including a first effector molecule covalently joined to a first nucleic acid, and a second supramolecular component including a second effector molecule covalently joined to a second nucleic acid, wherein the second nucleic acid has a region of at least partial complementarity to the first nucleic acid, wherein the first nucleic acid is in a base pairing relationship with the second nucleic acid and the first or second effector molecules are proteins, polypeptides, lipids or sugars. The supramolecule may further have a third supramolecule component which includes a third effector molecule covalently joined to a third nucleic acid, wherein the third nucleic acid has a region of at least partial complementary to the first nucleic acid or the second nucleic acid and wherein the third nucleic acid is in a base pairing relationship with the second nucleic acid or the first nucleic acid.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.