Inhibition of viral infection and spread with viral and RhoA-derived peptides
US6814968B1 · kind B1 · utility
3Cited by
1References
2Claims
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Key dates
| Filing date | Aug 5, 1998 |
| Grant date | Nov 9, 2004 |
| Priority date | — |
| Expiry date | Aug 5, 2018 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2760/18522
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Isolated peptides, peptidomimetics, and antibodies which bind to the viral fusion protein binding domain of the RhoA protein or the RhoA binding domain of a viral fusion protein are useful for inhibiting infection in susceptible cells, in vitro and in vivo. Among these viruses are the Paramyxovirus respiratory syncytial virus (RSV) and the Lentivirus human immunodeficiency virus (HIV).
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.