Microspheres containing condensed polyanionic bioactive agents and methods for their production
US6814980B2 · kind B2 · utility
91Cited by
4References
5Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 4, 2002 |
| Grant date | Nov 9, 2004 |
| Priority date | — |
| Expiry date | Apr 4, 2022 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K9/5192
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to novel compositions comprising microspheres and/or nanospheres containing condensed polyanionic bioactive agents, such as DNA. The polyanionic bioactive agent in the microspheres and/or nanospheres is preferably condensed using a polycationic condensing agent, such as poly-L-lysine. The present invention further relates to methods for producing the microspheres and/or nanospheres containing condensed polyanionic bioactive agents.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.