Human peroxisome proliferator activated receptor &ggr; compositions and methods
US6815168B1 · kind B1 · utility
Inventors
Key dates
| Filing date | Jun 1, 2000 |
| Grant date | Nov 9, 2004 |
| Priority date | — |
| Expiry date | Sep 11, 2021 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K14/70567
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The invention relates generally to compositions of and methods for obtaining peroxisome proliferator-activated receptors. The invention relates as well to the DNA sequences encoding peroxisome proliferator-activated receptors, the recombinant vectors carrying those sequences, the recombinant host cells including either the sequences or vectors, and recombinant peroxisome proliferator-activated receptor polypeptides. By way of example, the invention discloses the cloning and functional expression of a peroxisome proliferator-activated receptor, designated PPAR-&ggr;, obtained from a human source. The invention includes as well, methods for using the isolated, recombinant peroxisome proliferator-activated receptor polypeptides in assays designed to select and improve substances capable of interacting with peroxisome proliferator-activated receptor polypeptides for use in diagnostic, drug design and therapeutic applications.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.