Nucleotide sequences encoding o-succinylhomoserine sulfhydrylase

US6815196B2 · kind B2 · utility

Assignee

• Degussa AG · DE

Inventors

• Brigitte Bathe · Salzkotten, DE
• Walter Pfefferle · Bodenwerder, DE
• Klaus Huthmacher · Gelnhausen, DE
• Christian Rueckert · Vellmar, DE
• Joern Kalinowski · Bielefeld, DE
• Alfred Puehler · Bielefeld, DE
• Michael Binder · Steinhagen, DE
• Dieter Greissinger · Florstadt, DE
• Georg Thierbach · Bielefeld, DE

Key dates

• Filing date: Aug 2, 2001
• Grant date: Nov 9, 2004
• Expiry date: Feb 13, 2022

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12P13/12
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

The present invention relates to isolated polynucleotides from Corynebacterium glutamicum encoding proteins of the transcription activator (MetR) and O-succinylhomoserine sulfhydrylase (MetZ). The invention also relates to producing L-amino acids, particularly methionine, in coryneform cells having attenuated metR and metZ genes.