Patent · US Expired

1,2,3,4-Tetrahydroisoquinolines derivatives as urotensin II receptor antagonists

US6815451B2 · kind B2 · utility

1Cited by

1References

18Claims

0Family size

Assignee

Actelion Pharmaceuticals Ltd. · CH

Inventors

Jorg Velker · Huningue, FR
Hamed Aissaoui · Allschwil, CH
Christoph Binkert · Basel, CH
Martine Clozel · Binningen, CH
Boris Mathys · Egerkingen, CH
Claus Mueller · Allschwil, CH
Oliver Nayler · Arlesheim, CH
Michael Scherz · Ettingen, CH
Thomas Weller · Binningen, CH

Key dates

Filing date	Sep 15, 2003
Grant date	Nov 9, 2004
Priority date	—
Expiry date	Sep 15, 2023

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D491/04
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The invention relates to novel 1,2,3,4-tetrahydroisoquinoline derivatives of formula (I) and related compounds and their use as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including processes for the preparation of the compounds, pharmaceutical compositions containing one or more of those compounds and especially their use as neurohormonal antagonists especially urotensin II antagonists.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.