In situ polymerizable hydrogels
US6818018B1 · kind B1 · utility
Assignee
Inventor
Key dates
| Filing date | Aug 14, 1998 |
| Grant date | Nov 16, 2004 |
| Priority date | — |
| Expiry date | Aug 14, 2018 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S623/926
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
Compositions and methods for forming hydrogels in situ through a combination of physical and chemical crosslinking processes are provided in which physical crosslinking is mediated by one or more natural or synthetic components that stabilize the a hydrogel-forming precursor solutions at a deposition site for a period of time sufficient for more resilient chemical crosslinks to form. Methods of using such hydrogels as tissue coatings to prevent postsurgical adhesion formation, as tissue augmentation or luminal occlusion aids, as matrices for carrying cells, drugs or other bioactive species, as tissue sealants or adhesives, and as medical device coatings also are provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.