Patent · US Expired

Use of perfluoroalkyl-containing metal complexes as contrast media in MR-imaging for visualization of plaque, tumors and necroses

US6818203B2 · kind B2 · utility

5Cited by

2References

35Claims

0Family size

Assignee

SCHERING CORPORATION · US

Inventors

Johannes Platzek · Berlin, DE
Peter Mareski · Berlin, DE
Ulrich Niedballa · Berlin, DE
Bernd Raduechel · Berlin, DE
Hanns-Joachim Weinmann · Berlin, DE
Bernd Misselwitz · Berlin, DE

Key dates

Filing date	Aug 10, 2001
Grant date	Nov 16, 2004
Priority date	—
Expiry date	Sep 2, 2021

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61K49/085
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The invention relates to the use of perfluoroalkyl-containing metal complexes that have a critical micelle formation concentration <10−3 mol/l, a hydrodynamic micelle diameter (2 Rh)>1 nm and a proton relaxivity in plasma (R1)>10 l/mmol·s) as contrast media in MR imaging for visualization of plaque, lymph nodes, infarcted and necrotic tissue and for independent visualization of necrotic tissue and tumor tissue.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.