Anti-endotoxic antimicrobial cationic peptides and methods of use therfor
US6818407B2 · kind B2 · utility
21Cited by
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21Claims
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Key dates
| Filing date | Jul 17, 2001 |
| Grant date | Nov 16, 2004 |
| Priority date | — |
| Expiry date | Dec 25, 2022 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02A50/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A novel class of cationic peptides having antimicrobial activity is provided. Exemplary peptides of the invention include KWKSFIKKLTSAAKKVVTTAKPLALIS (SEQ ID NO:3) and KGWGSFFKKAAHVGKHVGKAALTHYL (SEQ ID NO:15). Also provided are methods for inhibiting the growth of bacteria utilizing the peptides of the invention. Such methods are useful for the treatment of respiratory infections, such as in cystic fibrosis patients. Such methods are further useful for accelerating wound healing.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.