Melvinolin derivatives

US6818638B2 · kind B2 · utility

Assignee

• Novartis AG · CH

Inventors

• Rolf Baenteli · Basel, CH
• Wilfried Bauer · Lampenberg, CH
• Sylvain Cottens · Witterswil, CH
• Claus Ehrhardt · Lörrach, DE
• Ulrich Hommel · Mülheim, DE
• Jörg Kallen · Basel, CH
• Josef Gottfried Meingassner · Wien, AT
• Francois Nuninger · Wittenheim, FR
• Gabriele Weitz Schmidt · Bad Krozingen, DE

Key dates

• Filing date: Jul 11, 2002
• Grant date: Nov 16, 2004
• Expiry date: Jul 11, 2022

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07C2602/28
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Mevinolin derivatives wherein the lactone ring is modified have interesting pharmaceutical properties, particularly in preventing or treating disorders or diseases mediated by LFA-1/ICAM-1 interactions.