(Dihydro) isoquinoline derivatives as phosphodiesterase inhibitors

US6818651B2 · kind B2 · utility

Assignee

• ALTANA PHARMA AG · DE

Inventors

• Steffen Weinbrenner · Konstanz, DE
• Beate Schmidt · Allensbach, DE
• Gerhard Grundler · Konstanz, DE
• Josef Stadlwieser · Konstanz, DE
• Armin Hatzelmann · Konstanz, DE
• Geert Jan Sterk · Utrecht, NL

Key dates

• Filing date: Aug 21, 2003
• Grant date: Nov 16, 2004
• Expiry date: Aug 21, 2023

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D513/04
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

3,4-Dihydroisoquinoline and isoquinoline compounds of formula I, in which Ar represents a phenyl raidcal of the formulae IIa, IIb or IIc are novel effective PDE7 inhibitors.