5-alkyl-7-alkylcarbonate-isoflavone ester and related method
US6818668B2 · kind B2 · utility
Assignee
Inventor
Key dates
| Filing date | Apr 12, 2002 |
| Grant date | Nov 16, 2004 |
| Priority date | — |
| Expiry date | May 25, 2022 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P21/06
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A compound is provided for increasing the concentration of a parent isoflavone in a subject in vivo. The parent isoflavone has a skeletal structure including a 5 position and a 7 position, a 5 alkyl group, and a 7-hydroxy group with a 7-hydroxy oxygen appended to the 7 position and a 7-hydroxy hydrogen appended to the 7-hydroxy oxygen. The compound includes a substrate having the skeletal structure of the parent isoflavone, with a 5 position and a 7 position corresponding to the 5 and 7 positions respectively of the parent isoflavone. An alkyl group is appended to the 5 position. A promoiety is appended to the 7-hydroxy oxygen of the substrate as a substitute for the 7-hydroxy hydrogen of the parent isoflavone, the promoiety and the 7-hydroxy oxygen establishing an alkylcarbonate ester. A related method also is provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.