Removal of dye-labeled dideoxy terminators from DNA sequencing reactions
US6818760B1 · kind B1 · utility
8Cited by
9References
50Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Oct 6, 2000 |
| Grant date | Nov 16, 2004 |
| Priority date | — |
| Expiry date | Nov 14, 2020 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q1/6844
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
This invention provides methods for removing unincorporated dye-labeled molecules from a mixture that includes dye-labeled polynucleotides or other polymers and the unincorporated dye-labeled molecules. The methods involve adsorbing the unincorporated dye-labeled molecules into a plurality of particles that are made up of one or more porous hydrophobic materials that are encapsulated in a hydrophilic matrix.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.