Method for screening for drug candidates for modulating transcription factor activity
US6821737B2 · kind B2 · utility
2Cited by
28References
15Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Jun 8, 2001 |
| Grant date | Nov 23, 2004 |
| Priority date | — |
| Expiry date | Jan 1, 2022 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N33/6845
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Method and kits are provided for screening for transcription factor modulators efficiently. In one aspect, the method can be employed to profile multiple, different transcription factors activated in a sample in the presence of each of the transcription factor modulators. Comparison of the activated transcription factor profiles in the presence and absence of the modulator identifies the transcription factor modulator that modulates the activation of specific transcription factors.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.