Processes for making pharmaceutical oral ECB formulations and compositions
US6821951B2 · kind B2 · utility
13Cited by
33References
21Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Aug 29, 2001 |
| Grant date | Nov 23, 2004 |
| Priority date | — |
| Expiry date | Nov 22, 2021 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02A50/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A fluid bed spray process is described where one or more carbohydrates are incorporated into an echinocandin formulation to provide a significant improvement in thermal stability. The carbohydrate is solubilized with an echinocandin compound or echinocandin/carbohydrate complex in a solvent(s) to form a pharmaceutical solution which is sprayed onto the surface of a granular diluent or carrier. The resulting granular oral formulations and medicaments derived therefrom are also described.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.