Designed protein pores as components for biosensors
US6824659B2 · kind B2 · utility
125Cited by
5References
25Claims
0Family size
Assignee
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Key dates
| Filing date | Feb 15, 2001 |
| Grant date | Nov 30, 2004 |
| Priority date | — |
| Expiry date | Aug 21, 2021 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K14/31
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A mutant staphylococcal alpha hemolysin polypeptide containing a heterologous analyte-binding amino acid which assembles into an analyte-responsive heptameric pore assembly in the presence of a wild type staphylococcal alpha hemolysin polypeptide, digital biosensors, and methods of detecting, identifying, and quantifying analytes are described.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.