Detection of antibodies to gangliosides using solid-phase reactants coated with carbonyl groups
US6824999B1 · kind B1 · utility
1Cited by
4References
19Claims
0Family size
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Key dates
| Filing date | May 5, 2000 |
| Grant date | Nov 30, 2004 |
| Priority date | — |
| Expiry date | May 5, 2020 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2405/10
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Methods of detecting antibodies to one or more ganglioside(s) of interest in a sample are disclosed which comprise using a solid-phase reactant having carbonyl groups attached thereon, and the ganglioside(s) of interest linked to the solid-phase reactant by an amide bond between an amino group of the ganglioside of interest and a carbonyl group attached to the solid-phase reactant. The methods of detecting antibodies to ganglioside(s) of interest can be used in methods of diagnosing neuropathies in an individual.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.