Cyclic lipopeptide acylase
US6825003B2 · kind B2 · utility
0Cited by
7References
2Claims
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Assignee
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Key dates
| Filing date | Jan 18, 2002 |
| Grant date | Nov 30, 2004 |
| Priority date | — |
| Expiry date | Nov 19, 2022 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides a cyclic lipopeptide acylase which may effectively deacylate the acyl side chain of a cyclic lipopeptide compound, specifically FR901379 Substance or its analog thereof shown by the following general formula [I], and a process for production of a cyclic peptide compound which comprises the use of said acylase. [wherein R1 is acyl;R2 is hydroxy or acyloxy;R3 is hydrogen or hydroxy;R4 is hydrogen or hydroxy;R5 is hydrogen or hydroxysulfonyloxy; andR6 is hydrogen or carbamoyl]
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.