Therapeutic and diagnostic methods and compositions based on Jagged/Notch proteins and nucleic acids
US6825007B2 · kind B2 · utility
8Cited by
3References
14Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Aug 6, 2002 |
| Grant date | Nov 30, 2004 |
| Priority date | — |
| Expiry date | Aug 6, 2022 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K48/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
This invention relates to therapeutic and diagnostic methods and compositions based on Jagged/Notch proteins and nucleic acids, and on the role of their signaling pathway in endothelial cell migration and/or differentiation. In addition, this invention provides a substantially purified Jagged protein, as well as a substantially purified nucleic acid molecule or segment thereof encoding Jagged protein, or a functionally equivalent derivative, or allelic or species variant thereof.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.