Copolymers and preparation thereof
US6825308B1 · kind B1 · utility
Assignee
Inventors
Key dates
| Filing date | Oct 29, 2003 |
| Grant date | Nov 30, 2004 |
| Priority date | — |
| Expiry date | Oct 29, 2023 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC08F220/60
- WIPO fieldMacromolecular chemistry, polymers
- WIPO sectorChemistry
Abstract
The present invention relates to copolymers for applications in medicine and biotechnology and preparation thereof. Copolymers comprises polyvalent N-Acetyl Glucosamine(NAG) in polyvalent form and bind more efficiently to lysozyme than NAG itself. The copolymers exhibit effective inhibition even at very low ligand concentrations. The copolymers could be used for prevention and treatment of bacterial and viral infections. Moreover, these copolymers form are stimuli sensitive polymers and can be used for the recovery of biomolecules. The methodology can be extended to other ligands such as sialic acid and used for preventing influenza and/or rotavirus infections. It also provides a method for the synthesis of copolymers wherein polymers comprising sequences of specific ligands are required.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.