EPTFE covering for endovascular prostheses and method of manufacture
US6827737B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Sep 25, 2001 |
| Grant date | Dec 7, 2004 |
| Priority date | — |
| Expiry date | Feb 10, 2022 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61L2300/602
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
An implantable composite device for regulated delivery of bioactive agents to the site of implantation includes at least two zones of distinct porosities through its cross-section. One zone is of a sufficient porosity to permit regulated transport of bioactive agents associated with the device to an area of the body in need of treatment. The bioactive agent associated with the device can be either a therapeutic or diagnostic agent. In a particular embodiment of the invention, the device includes a tubular body consisting of a first luminal layer of ePTFE having a porosity sufficient to promote cell endothelization along the luminal surface; and a second polymeric layer disposed on the first layer of a porosity permitting regulated transport of the bioactive agents.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.