Epoxide hydrolases from streptomyces

US6828115B1 · kind B1 · utility

Assignee

• BASF SE

Inventors

• Frank Zocher · Frankfurt am Main, DE
• Markus Enzelberger · Gräfelfing, DE
• Rolf Schmid · Gelterkinden, CH
• Wolfgang Wohlleben · Bielefeld, DE
• Bernhard Hauer · Neheim, DE

Key dates

• Filing date: Jan 23, 2002
• Grant date: Dec 7, 2004
• Expiry date: Apr 29, 2022

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12P41/00
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

A description is given of epoxide hydrolases from bacteria of the genus Streptomyces, a novel process for the enzymatic separation of epoxide enantiomeric mixtures, of a novel detection method for epoxide hydrolase activity, a screening method for detecting epoxide hydrolase activity and the use of bacteria of the genus Streptomyces and of the resultant epoxide hydrolases for enantioselective epoxide hydrolysis.