Compositions and methods for the therapy and diagnosis of breast cancer

US6828431B1 · kind B1 · utility

Assignee

• CORIXA CORPORATION · US

Inventors

• Tony Frudakis · Sarasota, US
• Steven G. Reed · Bellevue, US
• John M. Smith · Everett, US
• Lynda Misher · Seattle, US
• Davin C. Dillon · Issaquah, US
• Marc Retter · Carnation, US
• Aijun Wang · Davis, US
• Yasir Skeiky · Bellevue, US
• Susan Harlocker · Foster City, US

Key dates

• Filing date: Oct 26, 2000
• Grant date: Dec 7, 2004
• Expiry date: Dec 24, 2020

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y10S436/813
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Compositions and methods for the therapy and diagnosis of cancer, particularly breast cancer, are disclosed. Illustrative compositions comprise one or more breast tumor polypeptides, immunogenic portions thereof, polynucleotides that encode such polypeptides, antigen presenting cell that expresses such polypeptides, and T cells that are specific for cells expressing such polypeptides. The disclosed compositions are useful, for example, in the diagnosis, prevention and/or treatment of diseases, particularly breast cancer.