Method for producing acyl amino acids

US6828452B2 · kind B2 · utility

Assignee

• Cognis Deutschland GmbH & Co. KG · DE

Inventors

• Hans-Christian Raths · Monheim, DE
• Andreas Syldath · Goldkronach, DE
• Karl Schmid · Mettmann, DE
• Juergen Falkowski · Monheim, DE
• Ingomar Mrozek · Goldkronach, DE
• Josef Koester · Goldkronach, DE

Key dates

• Filing date: Jul 15, 2003
• Grant date: Dec 7, 2004
• Expiry date: Jul 15, 2023

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C11D1/52
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Acylamino acids are made by a process which comprises the steps of: (1) introducing a mixture comprised of at least one amino acid or amino acid salt and an alkali source into a reaction zone; (2) adding a mixture comprised of a fatty acid halide of the formula (I):R1COX  (I)wherein R1 is an alkyl or alkenyl group having from 6 to 22 carbon atoms and X is chlorine, bromine or iodine to form a reaction mixture while continuously circulating the reaction mixture from the reaction zone through a mixing zone until all of the second mixture has been added to the reaction zone. The process guarantees uniform mixing of the reaction components without the foaming observed without the use of a mixing zone.