Reduction of oxidative stress factors with Lactobacillus plantarum
US6830750B1 · kind B1 · utility
6Cited by
5References
12Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Apr 26, 2001 |
| Grant date | Dec 14, 2004 |
| Priority date | — |
| Expiry date | Apr 26, 2021 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P43/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention refers to the use of a bacterial strain, preferably of the genus Lactobacillus or Propionibacterium, giving rise to increased amounts of propionic acid in the gut for the manufacture of a medicament for reduction of the level of oxidative stress factors, such as IL-6, reactive oxygen species (ROS), and adhesion molecules in mammals including man. The medicament can be used for the prophylaxis and/or treatment of chronic inflammatory diseases such as rheumatic diseases and psoriasis.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.