Common neural progenitor for the CNS and PNS
US6830927B2 · kind B2 · utility
19Cited by
4References
4Claims
0Family size
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Key dates
| Filing date | May 6, 1998 |
| Grant date | Dec 14, 2004 |
| Priority date | — |
| Expiry date | May 6, 2018 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2506/08
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A method of generating neural crest stem cells involves inducing neuroepithelial stem cells to differentiate in vitro into neural crest stem cells. Differentiation can be induced by replating the cells on laminin, withdrawing mitogens, or adding dorsalizing agents to the growth medium. Derivatives of the peripheral nervous system can be generated by inducing the neural crest stem cells to differentiate in vitro.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.