Pyrazoline derivative or tetrahydropyridazine derivative and medicinal use thereof
US6831083B2 · kind B2 · utility
2Cited by
0References
9Claims
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Key dates
| Filing date | Sep 20, 2002 |
| Grant date | Dec 14, 2004 |
| Priority date | — |
| Expiry date | Jan 2, 2023 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D495/04
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Using a compound selected from compounds represented by the following formula (1) (which include 3-phenyl-2-pyrazoline derivatives and 3-phenyl-tetrahydropyridazine derivatives) and pharmacologically acceptable salts thereof, an agent is provided which can activate glutamic acid transporter and which is useful for prevention and/treatment of cerebral ischemia (cerebral infarct and brain edema), amyotrophic lateral sclerosis (ALS), etc., all caused by glutamic acid toxicity.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.