Process for producing transglutaminase
US6833258B2 · kind B2 · utility
12Cited by
2References
39Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 28, 2001 |
| Grant date | Dec 21, 2004 |
| Priority date | — |
| Expiry date | Jun 28, 2021 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Y203/02013
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention relates to a high-yield process for producing high-activity, high-purity transglutaminase by refolding denatured microorganism-derived transglutaminase by reacting denatured transglutaminase in an aqueous medium under acidic conditions and reconstituting a higher-order enzymatically active state in an aqueous medium at a neutral pH.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.