Nucleosides having bicyclic sugar moiety
US6833361B2 · kind B2 · utility
166Cited by
1References
11Claims
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Key dates
| Filing date | Apr 30, 2002 |
| Grant date | Dec 21, 2004 |
| Priority date | — |
| Expiry date | Apr 30, 2022 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07H19/16
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Conformationally restricted 2′, 4′-bridged nucleoside analogues are described herein. The compounds can be prepared by cyclization at C2′ and C4′ of nucleosides through a linker or linking molecule. These novel nucleosides have a desired, locked sugar pucker and are potentially useful as pharmaceutical ingredients, and especially for use in treatment of HCV.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.