1, 2, 5, 10-tetrahydropyridazino[4, 5-b]quinoline-1,10-diones and their use for the treatment of pain

US6833368B2 · kind B2 · utility

Assignee

• ASTRAZENECA AB · SE

Inventors

• Megan Murphy · Wilmington, US
• Wenhua Xiao · Wilmington, US
• Dean Brown · Wilmington, US
• Rebecca Urbanek · Wilmington, US
• Frances M. McLaren · Wilmington, US
• Edward Vacek · Wilmington, US
• Thomas Bare · West Chester, US
• Carey Horchler · Wayne, US
• Christine Barlaam · Reims, FR
• Gary Steelman · Wilmington, US
• Vernon Alford · Raritan, US

Key dates

• Filing date: Oct 9, 2003
• Grant date: Dec 21, 2004
• Expiry date: Oct 9, 2023

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P29/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Compounds useful for the treatment of pain in accord with structural diagram (I), or tautomers or pharmaceutically-acceptable salts of such compounds, wherein R1 and A are as disclosed in the specification. Also disclosed are methods for the treatment of pain using compounds according to structural diagram (I) and pharmaceutical compositions comprising compounds according to structural diagram (I).