Bottle-brush type coatings with entangled hydrophilic polymer
US6835410B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | May 9, 2002 |
| Grant date | Dec 28, 2004 |
| Priority date | — |
| Expiry date | May 9, 2022 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61L27/34
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
The invention relates to a process for coating a material surface comprising the steps of:(a) providing an inorganic or organic bulk material having covalently bound to its surface initiator moieties for radical polymerization;(b) graft polymerizing a hydrophilic ethylenically unsaturated macromonomer from the bulk material surface in the presence of a biocompatible hydrophilic polymer being devoid of polymerizable ethylenically unsaturated groups and thereby entrapping said hydrophilic polymer within the polymer matrix formed by the polymerization of the macromonomer.Composite materials obtainable according to the process of the invention have desirable characteristics regarding adherence to the substrate, durability, hydrophilicity, wettability, biocompatibility and permeability and are thus useful for the manufacture of biomedical articles such as ophthalmic devices.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.