Useful mutations of bacterial alkaline protease
US6835821B2 · kind B2 · utility
10Cited by
5References
15Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 5, 2002 |
| Grant date | Dec 28, 2004 |
| Priority date | — |
| Expiry date | Jul 9, 2023 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N9/54
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention relates to mutations of a subtilisin gene which result in changes in the chemical characteristics of subtilisin enzymes. Mutations at specific nucleic acids of the subtilisin gene result in amino acid substitutions and consequently, altered enzyme function. Some of these mutant enzymes exhibit physical properties advantageous to industrial applications, particularly in the detergent industry, providing subtilisin which is more stable to oxidation, possesses greater protease activity, and exhibits improved washability.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.