Allelic series of genomic modifications in cells
US6835867B1 · kind B1 · utility
2Cited by
5References
7Claims
0Family size
Inventors
Key dates
| Filing date | Jun 24, 1998 |
| Grant date | Dec 28, 2004 |
| Priority date | — |
| Expiry date | Jun 24, 2018 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N15/01
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention relates to methods of producing an allelic series of modifications in genes of interest in a cell. In particular, the invention provides methods for using nucleic acid sequence-modifying agents (e.g., chemicals, electromagnetic radiation, etc.) to introduce modifications in any nucleic acid sequence in the genome of a cell. Also provided are sets of cells which contain at least one modification in any gene of interest. The methods and compositions of the invention are useful in determining the function of the gene of interest.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.