Inhaleable spray dried 4-helix bundle protein powders having minimized aggregation
US6838075B2 · kind B2 · utility
50Cited by
42References
27Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 14, 2003 |
| Grant date | Jan 4, 2005 |
| Priority date | — |
| Expiry date | Mar 14, 2023 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC09D11/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides highly dispersible spray-dried powder compositions, and in particular, inhaleable dry powder compositions for aerosolized delivery to the lungs. The powders of the invention are produced by spray drying a 4 α-helix bundle protein under conditions which both (i) protect the protein from aggregation and (ii) provide particles suitable for inhalation (i.e., demonstrating superior aerosol performance).
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.